| Issue |
BioMedicine
Volume 9, Number 1, March 2019
|
|
|---|---|---|
| Article Number | 2 | |
| Number of page(s) | 12 | |
| DOI | https://doi.org/10.1051/bmdcn/2019090102 | |
| Published online | 22 February 2019 | |
Review article
Materials and structures used in meniscus repair and regeneration: a review
Centre of Excellence for Medical Textiles, The South India Textile Research Association, Coimbatore, Tamilnadu, India
* Corresponding author. The South India Textile Research Association, Coimbatore, Tamilnadu, 641014 India. E-mail address: kvarticles@live.co.uk (K. Vadodaria).
Received:
12
October
2018
Accepted:
19
December
2018
Meniscus is a vital functional unit in knee joint. It acts as a lubricating structure, a nutrient transporting structure, as well as shock absorber during jumping, twisting and running and offers stability within the knee joint. It helps in load distribution, in bearing the tensile hoop stresses and balancing by providing a cushion effect between hard surfaces of two bones. Meniscus may be injured in sports, dancing, accident or any over stressed condition. Any meniscal lesion can lead to a gradual development of osteoarthritis or erosion of bone contact surface due to disturbed load and contact stress distribution caused by injury/pain. Once injured, the possibilities of self-repair are rare in avascular region of meniscus, due to lack of blood supply in avascular region. Meniscus has vascular and avascular regions in structure. Majority of the meniscus parts turn avascular with increase in age.
Purpose of this review is to highlight advances in meniscus repair with special focus on tissue engineering using textile/fiber based scaffolds, as well as the recent technical advances in scaffolds for meniscus recon- struction/ regeneration treatment.
Key words: Meniscus / Biomaterial / Regeneration / Scaffold / Textile / Tissue engineering
© Author(s) 2019. This article is published with open access by China Medical University
Open Access This article is distributed under terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided original author(s) and source are credited.