Volume 9, Number 1, March 2019
|Number of page(s)||4|
|Published online||22 February 2019|
Early post-surgical recurrence of metastatic vertebral neuro-endocrine tumour treated effectively with chemo-radiotherapy
Department of Orthopaedic Surgery, Spine Division, Tan Tock Seng Hospital, Singapore
2 Department of Orthopaedic Surgery, Melmaruvathur Adhiparasakthi Institute of Medical Sciences and Research, Melmaruvathur, Tamil Nadu, India
3 Department of Pathology, Tan Tock Seng Hospital, Singapore
* Corresponding author. Department of Orthopaedic Surgery, Spine Division, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433. E-mail address: Jacob_Oh@yahoo.com (J. Y. L. Oh).
Accepted: 17 October 2018
Spinal metastasis of neuro-endocrine tumours (NETs) usually arise from a primary in the lung. We encountered such a patient with NET metastasis to T6 vertebra causing severe cord compression. Considering the neurological status, immediate decompression surgery along with T3-T8 posterior stabilization was done. Early recurrence of the tumour causing near total obliteration of the spinal canal leading to significant neurological compromise was noted within one month of surgery. A second surgery at this stage was avoided due to the risk involved and concurrent chemo-radiotherapy was initiated. The tumour was sensitive to chemo-radiotherapy and rapid resolution was noted on subsequent follow-up visits. With appropriate rehabilitation, patient regained full power to become ambulant with support. This case report highlights a rare, early and aggressive recurrence of metastatic vertebral NET following index surgery which was effectively managed with chemo-radiotherapy.
Key words: Metastasis / Myelopathy / Neuroendocrine tumours / Spinal cord compression / Concurrent chemoradiotherapy
© Author(s) 2019. This article is published with open access by China Medical University
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