| Issue |
BioMedicine
Volume 9, Number 3, September 2019
|
|
|---|---|---|
| Article Number | 17 | |
| Number of page(s) | 7 | |
| DOI | https://doi.org/10.1051/bmdcn/2019090317 | |
| Published online | 27 August 2019 | |
Original article
Development of broad spectrum mycosporine loaded sunscreen formulation from Ulva fasciata delile
1
Amity institute of pharmacy, Amity University Haryana, Gurgaon, Haryana - 122413, India
2
Amity Institute of Pharmacy, Amity University Madhya Pradesh, Maharajpura, Gwalior (MP) - 474005, India
3
Departemnt of Pharmacy and Biochemistry, Centro Latinoamericano de Enseñanza e Investigación en Bacteriologia Alimentaria, National San Marcos University, Lima
Peru - 15081
4
Poona college of Pharmacy, Bharati Vidyapeeth Deemed University, Pune, Maharashtra - 411045, India
5
Faculty of Persian Traditional Medicine, Tabriz University of Medical, Sciences, Tabriz - 51368, Iran
*Corresponding author. Amity institute of pharmacy (AIP), Amity University Haryana, Gurgaon, India. E-mail address: sbsaurabhbhatia@gmail.com (S. Bhatia).
Received:
2
April
2019
Accepted:
2
May
2019
Ba.ckground: Sunscreen formulations primarily offer protection against UV induced damages however nowadays it also maintains skin natural physiological conditions. Current global market is flooded with numerous sunscreen products which offer protection to skin against several UV induced damages. However most of these sunscreen formulations offers narrow spectrum protection against UV and also suffer from stability as well as toxicity related issues.
Methods: Present work aims to isolate mycosporine amino acid (Mgy) from green alga namely Ulva fasciata (U. fasciata) and study its sunscreen potential against widely used domestic marketed formulation. Stability evaluations were also performed for almost 90 days.
Results: Results demonstrated that the isolated compound, mycosporine glycine (Mgy) preserved physicochemical properties of the product and offered good stability for all formulations throughout the experimental period. Furthermore, Mgy loaded carbopol gel showed better sunscreen protection against marketed formulation in a concentration dependent manner. (7.709).
Conclusion: (6.806) Novel Myg loaded gel was proved to demonstrate several quality characteristics that may unlock new prospects for the production of more efficient, safe, and economic skin-care products.
Key words: Ulva / Gel / Sunscreen / Ultraviolet / UV-B / Mycosporine amino acid / Broad spectrum / Ulva fasciata
© Author(s) 2019. This article is published with open access by China Medical University
Open Access This article is distributed under terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided original author(s) and source are credited.