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Table 1

Chararacteristics of acute pancreatitis cases and control subjects

Acute ancreatitis
Control subjects N = 27032
Cases N = 7577

Variable n (%) n (%) P value*
Sex 0.42
    Female 9072 33.6 2505 33.1
    Male 17960 66.4 5072 66.9
Age group (year) 0.33
    20-39 8149 30.2 2351 31.0
    40-64 13055 48.3 3617 47.7
    65-84 5828 21.6 1609 21.2
Age (year), mean (standard deviation) 50.3 15.7 50.1 15.7 0.39
  Etodolac 0.004
    Never used 27016 99.94 7564 99.82
    Active use 5 0.02 7 0.09
    Non-active use 11 0.04 6 0.08
  Other cyclooxygenase-2 inhibitors < 0.001
    Never used 21490 79.5 5628 74.3
    Have used 5542 20.5 1949 25.7
  Comorbidities before index date
    Alcohol-related disease 119 0.44 339 4.47 < 0.001
    Biliary stone 570 2.11 1563 20.6 < 0.001
    Cardiovascular disease 4859 18.0 1885 24.9 < 0.001
    Chronic kidney disease 481 1.78 322 4.25 < 0.001
    Chronic obstructive pulmonary disease 3400 12.6 1176 15.5 < 0.001
    Diabetes mellitus 2794 10.3 1509 19.9 < 0.001
    Hepatitis B 584 2.16 316 4.17 < 0.001
    Hepatitis C 275 1.02 188 2.48 < 0.001
    Hypertriglyceridemia 4701 17.4 2252 29.7 < 0.001

Data are presented as the number of subjects in each group, with percentages given in parentheses, or the mean with standard deviation given in parentheses.

*

Chi-square test and

t-test comparing subjects with and without acute pancreatitis.