The characteristics of individual reports investigating the genotypes of MMP1 promoter -1607 to gastric cancer risk.
|Author||Year||Population||Control, n||Case, n||Major findings|
|Mtsumura||2004||Japanese||166||215||MMP1 -1607 was not associated with GC risk, but may be markers for prognosis prediction such as lymph node metastasis and clinical stages.|
|Jin||2005||Mainland China||350||183||MMP1 -1607 was neither associated with GC risk nor prognostic indexes such as metastasis.|
|Fang||2010||Mainland China||252||246||There were no significant difference in the genotype or allele frequency of the MMP-1 16071G/2G between the case and control groups.|
|Devulapalli||2014||India||202||166||MMP1 -1607 was a determinant for GC risk, especially for those male gender, > 50 years, addicted to alcohol and smoking.|
|Dey||2014||India||145||145||MMP1 -1607 was not associated with GC risk. Other promoter SNPs on MMP1 may be markers for prognosis prediction such as metastasis.|
|Yang||current||Taiwanese||363||121||MMP1 -1607 was not associated with GC risk. It may interact with smoking and HP infection status determine the GC susceptibility.|