Open Access

Fig. 1

image

Download original image

Anti-apoptotic mechanism of phytoestrogen against extrinsic apoptosis: Similar to E2, phytoestrogens elevates the activity of PI3K-Akt to inhibit the JNK1/2 mediated activation and nuclear translocation of NFkB and thereby alleviates the LPS-induced cardiomyocyte apoptosis.