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Table 1

The biologic adverse reaction between ionic and non-ionic contrast media.

Biologic adverse reaction Ionic contrast media Non-ionic contrast media
Thermal effect Moderate Mild to less
Pain during injection Moderate Mild to less
Nausea and vomiting Moderate Mild to less
Toxicity to kidney Higher Lower
Tissue necrosis when extravasation occurs More severe Less severe
Other allergic effects Often (around 10%) Seldom (lower than 5%)