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Fig. 4

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Functional impacts of the dominant negative RSF-1 (RSF-D4). (a) Western blotting was performed to detect RSF-D4 expression in HeLa cells. Cells transfected with empty vectors were used as the negative control. RSF-1 functional knockdown by RSF-D4 (b) reduced cell growth and (c) increased paclitaxel sensitivity in HeLa cells.