Open Access

Table 1

Characteristics between cases with colorectal cancer and controls.

Controls N = 20218 Cases with colorectal cancer N = 20218

Variable n (%) n (%) P value*
Sex 0.10
 Female 9059 (44.8) 8897 (44.0)
 Male 11159 (55.2) 11321 (56.0)
Age group (years) 0.53
 20-39 110 (0.5) 115 (0.6)
 40-64 6777 (33.5) 6877 (34.0)
 65-84 13331 (66.0) 13226 (65.4)
Age (years), mean ± standard deviation 68.1 ± 9.6 68.2 ± 9.7 0.39
 Thiazolidinediones use 3818 (18.9) 3787 (18.7) 0.69
 Other anti-diabetic drugs use 16816 (83.2) 17546 (86.8) < 0.001
Comorbidities before index date
 Alcohol-related disease 1004 (4.97) 1151 (5.69) 0.001
 Cardiovascular disease 11475 (56.8) 11333 (56.1) 0.15
 Chronic kidney disease 3012 (14.9) 3015 (14.9) 0.97
 Chronic liver diseases 5187 (25.7) 5286 (26.2) 0.26
 Chronic obstructive pulmonary disease 5459 (27.0) 5469 (27.1) 0.91
 Colorectal adenoma 338 (1.67) 376 (1.86) 0.15
 Hyperlipidemia 11256 (55.7) 11222 (55.5) 0.73
 Hypertension 15914 (78.7) 15814 (78.2) 0.23
 Inflammatory bowel disease 329 (1.63) 375 (185) 0.08

Data are presented as the number of subjects in each group with percentages given in parentheses.

*

Chi-square test, and

t-test comparing cases with colorectal cancer and controls.