Open Access

Table 3

Odds ratio and 95% confidence interval of cumulative duration of thiazolidinediones use associated with colorectal cancer.

Variable Case number /control number Crude OR (95% CI) Adjusted OR (95% CI)
Never used thiazolidinediones as a reference 16431/16400 1.00 (reference) 1.00 (reference)
Cumulative duration of thiazolidinediones use (increase every one year) 3787/3818 1.00 (0.99, 1.001) 0.998 (0.997, 0.999)

Variables which were statistically associated with colorectal cancer in a univariable model were further included in a multivariable model. Only other anti-diabetic drugs and alcohol-related disease were included for adjustment.