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Table 3

Effects of GAE upon level (pg/mg protein) of IL-1beta, IL-6 and TNF-alpha. NGF differentiated-PC12 cells were pre-treated with GAE at 0.25%, 0.5% or 1%, and followed by using H2O2 to induce cell injury. Normal group had no GAE or H2O2. Control group had no GAE, but with H2O2. Data are mean ± sd (n = 7). a-eValues in a column without a common letter differ, P < 0.05.

IL-1beta IL-6 TNF-alpha
 Normal 10 ± 5a 9 ± 3a 8 ± 4a
 Control 76 ± 7d 79 ± 5d 91 ± 6e
GAE, 0.25 62 ± 4c 60 ± 6c 75 ± 4d
 GAE, 0.5 48 ± 2b 46 ± 4b 58 ± 3c
 GAE, 1 45 ± 4b 41 ± 3b 42 ± 4b