Open Access

Table 1

Comparative Evaluation of MAA-Carbopol gel against Marketed formulation.

Parameters MAA-Carbopol gel
Lotus gel (Marketed Preparation)
0 day 30 days 60 days 90 days
GSg (g/cm2) 377 ± 2.4 361 ± 1.3 377 ± 2.4 371 ± 2.1 417 ± 2.1

GT (°C) 27.3 ± 0.2 26.1 ± 0.1 26.8 ± 0.3 27.1 ± 0.1 25.4 ± 0.2

MT (°C) 71.7 ± 1.0 70.1 ± 1.3 71.3 ± 1.2 71.6 ± 1.1 67.1 ± 0.1

Apparent Viscosity (cp) at 80 °C 62.7 ± 1.3 61.7 ± 1.2 61.7 ± 1.5 61.8 ± 1.2 58.7 ± 0.2

MMS 21.1 ± 1.1 20.1 ± 1.0 22.1 ± 0.2 21.1 ± 1.1 17.1 ± 1.5

Ph 6.2 ± 0.07 6.2 ± 0.02 6.1 ± 0.04 6.1 ± 0.03 6.1 ± 0.01

Appearance White White White White White

Homogeneity Good Good Good Good Green

Spreading diameter (SD) after one minute (mm) 57 ± 0.1 58 ± 0.1 57 ± 0.2 58 ± 0.1 62 ± 0.2

Gelling strength (GS), gelling temperature (GT), melting temperature (MT), molecular weight (MW) determination, spread ability (SA), mycosprine amino acid (MAA), MMs (Molecular mass), Viscosity(cp), Spreading diameter (SD).