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Flowchart of the study design. The SAS cells were treated with 0.1% DMSO (control) or 50 μM fenofibrate for 24 hours. Then, the cells were collected for total RNA extraction and expression profiling. The results from DESeq2 analysis were further analyzed to identify genes with significantly differential expression according to the criteria of a fold change greater than 2 and a false discovery rate less than 0.05. Differentially expressed genes were selected for further cluster, GO, and KEGG enrichment analysis.